ea0099p507 | Endocrine-Related Cancer | ECE2024
Montero-Hidalgo Antonio J
, Vacas Juan Manuel Jimenez
, Gomez-Gomez Enrique
, Blazquez-Encinas Ricardo
, Sanchez-Sanchez Rafael
, Martinez-Fuentes Antonio Jesus
, Eyras Eduardo
, Castano Justo P
, Sharp Adam
, Olmos David
, Gahete Manuel D
, Luque Raul M
Prostate cancer (PCa) is one of the most common endocrine-related cancers (ERCs) among men worldwide. The aggressiveness of this tumor pathology is highly influenced by different endocrine-related factors, highlighting the crucial role of androgens. Therefore, the main therapeutic approach for PCa patients is based on the pharmacological blockade of androgen-signaling. However, some patients become unresponsive and develop a highly lethal castration-resistant disease, pointing...